Holger Rehmann: search on Z-Library

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1

Efficient Intracellular Delivery of Native Proteins

D’Astolfo, Diego S., Pagliero, Romina J., Pras, Anita, Karthaus, Wouter R., Clevers, Hans, Prasad, Vikram, Lebbink, Robert Jan, Rehmann, Holger, Geijsen, Niels

Journal:

Year:

2015

Language:

english

File:

PDF, 3.10 MB

english, 2015

2

Capturing cyclic nucleotides in action: snapshots from crystallographic studies

Rehmann, Holger, Wittinghofer, Alfred, Bos, Johannes L.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2007

Language:

english

File:

PDF, 974 KB

english, 2007

3

Structure and regulation of the cAMP-binding domains of Epac2

Rehmann, Holger, Prakash, Balaji, Wolf, Eva, Rueppel, Alma, de Rooij, Johan, Bos, Johannes L., Wittinghofer, Alfred

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 398 KB

english, 2002

4

Differences Between the Interaction of β-Catenin with Non-phosphorylated and Single-mimicked Phosphorylated 20-amino acid Residue Repeats of the APC Protein

Lara Tickenbrock, Katja Kößmeier, Holger Rehmann, Christian Herrmann, Oliver Müller

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 1.03 MB

english, 2003

5

The RapGEF PDZ-GEF2 is required for maturation of cell–cell junctions

Nadia Dubé, Matthijs R.H. Kooistra, Willem-Jan Pannekoek, Marjolein J. Vliem, Viola Oorschot, Judith Klumperman, Holger Rehmann, Johannes L. Bos

Journal:

Cellular Signalling

Year:

2008

Language:

english

File:

PDF, 1.50 MB

english, 2008

6

Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3

Hugo van Ingen, Frederik M.A. van Schaik, Hans Wienk, Joost Ballering, Holger Rehmann, Annemarie C. Dechesne, John A.W. Kruijzer, Rob M.J. Liskamp, H.Th. Marc Timmers, Rolf Boelens

Journal:

Year:

2008

Language:

english

File:

PDF, 1.79 MB

english, 2008

7

Photodynamic Therapy as Novel Nephron Sparing Treatment Option for Small Renal Masses

Kroeze, Stephanie G.C., Grimbergen, Mathijs C.M., Rehmann, Holger, Bosch, J.L.H. Ruud, Jans, Judith J.M.

Journal:

The Journal of Urology

Year:

2012

Language:

english

File:

PDF, 1.75 MB

english, 2012

8

Ras Association-Domain Dimers Bring Proteins Together

Rehmann, Holger, Bos, Johannes L.

Journal:

Year:

2016

Language:

english

File:

PDF, 445 KB

english, 2016

9

Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2

H.Bea Kuiperij, Johan de Rooij, Holger Rehmann, Miranda van Triest, Alfred Wittinghofer, Johannes L Bos, Fried J.T Zwartkruis

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2003

Language:

english

File:

PDF, 528 KB

english, 2003

10

[Methods in Enzymology] Regulators and Effectors of Small GTPases: Ras Family Volume 407 || Characterization of the Activation of the Rap‐Specific Exchange Factor Epac by Cyclic Nucleotides

Rehmann, Holger

Year:

2006

Language:

english

File:

PDF, 237 KB

english, 2006

11

Cover Picture: 8-pCPT-2′-O-Me-cAMP-AM: An Improved Epac-Selective cAMP Analogue (ChemBioChem 13/2008)

Marjolein J. Vliem, Bas Ponsioen, Frank Schwede, Willem-Jan Pannekoek, Jurgen Riedl, Matthijs R. H. Kooistra, Kees Jalink, Hans-Gottfried Genieser, Johannes L. Bos, Holger Rehmann

Journal:

Year:

2008

Language:

english

File:

PDF, 946 KB

english, 2008

12

Cyclic Nucleotide Mapping of Hyperpolarization-Activated Cyclic Nucleotide-Gated (HCN) Channels

Möller, Stefan, Alfieri, Andrea, Bertinetti, Daniela, Aquila, Marco, Schwede, Frank, Lolicato, Marco, Rehmann, Holger, Moroni, Anna, Herberg, Friedrich W.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 4.54 MB

english, 2014

13

10.1038/ncb1101-1020

Schmidt, Martina, Evellin, Sandrine, Weernink, Paschal A. Oude, Dorp, Frank vom, Rehmann, Holger, Lomasney, Jon W., Jakobs, Karl H.

Journal:

Nature Cell Biology

Year:

2001

Language:

english

File:

PDF, 201 KB

english, 2001

14

cNMP-AMs mimic and dissect bacterial nucleotidyl cyclase toxin effects

Beckert, Ulrike, Grundmann, Manuel, Wolter, Sabine, Schwede, Frank, Rehmann, Holger, Kaever, Volkhard, Kostenis, Evi, Seifert, Roland

Journal:

Biochemical and Biophysical Research Communications

Year:

2014

Language:

english

File:

PDF, 1.01 MB

english, 2014

15

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex.

van den Berg, Maaike C. W., van Gogh, Inkie J. A., Smits, Alida M. M., van Triest, Miranda, Dansen, Tobias B., Visscher, Marieke, Polderman, Paulien E., Vliem, Marjolein J., Rehmann, Holger, Burgering

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 581 KB

english, 2016

16

cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic β cells and rat INS-1 cells

Guoxin Kang, Oleg G. Chepurny, Brian Malester, Michael J. Rindler, Holger Rehmann, Johannes L. Bos, Frank Schwede, William A. Coetzee, George G. Holz

Journal:

The Journal of Physiology

Year:

2006

Language:

english

File:

PDF, 832 KB

english, 2006

17

Epac2: a sulfonylurea receptor?

Rehmann, Holger

Journal:

Biochemical Society Transactions

Year:

2012

Language:

english

File:

PDF, 278 KB

english, 2012

18

The guanine nucleotide exchange factor Rlf interacts with SH3 domain-containing proteins via a binding site with a preselected conformation

Popovic, Milica, Jakobi, Arjen J., Rensen-de Leeuw, Marije, Rehmann, Holger

Journal:

Journal of Structural Biology

Year:

2013

Language:

english

File:

PDF, 1.57 MB

english, 2013

19

Bmp and Nodal Independently Regulate lefty1 Expression to Maintain Unilateral Nodal Activity during Left-Right Axis Specification in Zebrafish

Smith, Kelly A., Noël, Emily, Thurlings, Ingrid, Rehmann, Holger, Chocron, Sonja, Bakkers, Jeroen, Mullins, Mary C.

Journal:

Year:

2011

Language:

english

File:

PDF, 4.20 MB

english, 2011

20

Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

Rehmann, Holger, Das, Joost, Knipscheer, Puck, Wittinghofer, Alfred, Bos, Johannes L.

Journal:

Year:

2006

Language:

english

File:

PDF, 363 KB

english, 2006

21

Cyclic nucleotide analogs as probes of signaling pathways

Poppe, Heiko, Rybalkin, Sergei D, Rehmann, Holger, Hinds, Thomas R, Tang, Xiao-Bo, Christensen, Anne E, Schwede, Frank, Genieser, Hans-Gottfried, Bos, Johannes L, Doskeland, Stein O

Journal:

Year:

2008

Language:

english

File:

PDF, 98 KB

english, 2008

22

Identification of a Novel, Small Molecule Partial Agonist for the Cyclic AMP Sensor, EPAC1

Parnell, Euan, McElroy, Stuart P., Wiejak, Jolanta, Baillie, Gemma L., Porter, Alison, Adams, David R., Rehmann, Holger, Smith, Brian O., Yarwood, Stephen J.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.20 MB

english, 2017

23

Rap1 and Rap2 Antagonistically Control Endothelial Barrier Resistance

Pannekoek, Willem-Jan, Linnemann, Jelena R., Brouwer, Patricia M., Bos, Johannes L., Rehmann, Holger, Gottardi, Cara

Journal:

Year:

2013

Language:

english

File:

PDF, 722 KB

english, 2013

24

Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B

Rehmann, Holger, Arias-Palomo, Ernesto, Hadders, Michael A., Schwede, Frank, Llorca, Oscar, Bos, Johannes L.

Journal:

Year:

2008

Language:

english

File:

PDF, 641 KB

english, 2008

25

The Rap1 Guanine Nucleotide Exchange Factor C3G Is Required for Preservation of Larval Muscle Integrity in Drosophila melanogaster

Shirinian, Margret, Grabbe, Caroline, Popovic, Milica, Varshney, Gaurav, Hugosson, Fredrik, Bos, Hans, Rehmann, Holger, Palmer, Ruth H., Samakovlis, Christos

Journal:

Year:

2010

Language:

english

File:

PDF, 2.27 MB

english, 2010

26

Identification of a Loss-of-Function Mutation in the Context of Glutaminase Deficiency and Neonatal Epileptic Encephalopathy

Rumping, Lynne, Büttner, Benjamin, Maier, Oliver, Rehmann, Holger, Lequin, Maarten, Schlump, Jan-Ulrich, Schmitt, Bernhard, Schiebergen-Bronkhorst, Birgit, Prinsen, Hubertus C. M. T., Losa, Michele, F

Journal:

Year:

2018

Language:

english

File:

PDF, 548 KB

english, 2018

27

Selectivity of CDC25 Homology Domain-Containing Guanine Nucleotide Exchange Factors

Popovic, Milica, Rensen-de Leeuw, Marije, Rehmann, Holger

Journal:

Journal of Molecular Biology

Year:

2013

Language:

english

File:

PDF, 695 KB

english, 2013

28

[Handbook of Experimental Pharmacology] || Interaction of Epac with Non-canonical Cyclic Nucleotides

Rehmann, Holger

Year:

2015

Language:

english

File:

PDF, 254 KB

english, 2015

29

Functional characterisation of a novel class of in-frame insertion variants of KRAS and HRAS

Eijkelenboom, Astrid, van Schaik, Frederik M. A., van Es, Robert M., Ten Broek, Roel W., Rinne, Tuula, van der Vleuten, Carine, Flucke, Uta, Ligtenberg, Marjolijn J. L., Rehmann, Holger

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 2.18 MB

english, 2019

30

Rin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22

Barbara Woller, Susan Luiskandl, Milica Popovic, Barbara E.M. Prieler, Gloria Ikonge, Michaela Mutzl, Holger Rehmann, Ruth Herbst

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 2.18 MB

english, 2011

31

Ligand-mediated Activation of the cAMP-responsive Guanine Nucleotide Exchange Factor Epac

Rehmann, Holger, Schwede, Frank, Døskeland, Stein O., Wittinghofer, Alfred, Bos, Johannes L.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 946 KB

english, 2003

32

Signal transduction: Thumbs up for inactivation

Rehmann, Holger, Bos, Johannes L.

Journal:

Year:

2004

Language:

english

File:

PDF, 316 KB

english, 2004

33

The PI3K effector Arap3 interacts with the PI(3,4,5)P3 phosphatase SHIP2 in a SAM domain-dependent manner

Judith H. Raaijmakers, Laurence Deneubourg, Holger Rehmann, John de Koning, Zhongchun Zhang, Sonja Krugmann, Christophe Erneux, Johannes L. Bos

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 914 KB

english, 2007

34

Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control

Willem-Jan Pannekoek, Jantine J.G. van Dijk, On Ying A. Chan, Stephan Huveneers, Jelena R. Linnemann, Emma Spanjaard, Patricia M. Brouwer, Anne Jan van der Meer, Fried J.T. Zwartkruis, Holger Rehmann,

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 1.45 MB

english, 2011

35

A Membrane Permeable Prodrug of S223 for Selective Epac2 Activation in Living Cells

Xu, Yunjian, Schwede, Frank, Wienk, Hans, Tengholm, Anders, Rehmann, Holger

Journal:

Year:

2019

File:

PDF, 3.42 MB

2019

36

Dynamic interaction of cAMP with the rap guanine-nucleotide exchange factor epac1

Astrid Kraemer, Holger R. Rehmann, Robbert H. Cool, Christiane Theiss, Johan de Rooij, Johannes L. Bos, Alfred Wittinghofer

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 239 KB

english, 2001

37

GEFs and GAPs: Critical Elements in the Control of Small G Proteins

Johannes L. Bos, Holger Rehmann, Alfred Wittinghofer

Journal:

Year:

2007

Language:

english

File:

PDF, 43 KB

english, 2007

38

8-pCPT-2′-O-Me-cAMP-AM: An Improved Epac-Selective cAMP Analogue

Marjolein J. Vliem, Bas Ponsioen, Frank Schwede, Willem-Jan Pannekoek, Jurgen Riedl, Matthijs R. H. Kooistra, Kees Jalink, Hans-Gottfried Genieser, Johannes L. Bos, Holger Rehmann

Journal:

Year:

2008

Language:

english

File:

PDF, 238 KB

english, 2008

39

Cyclic AMP signalling in Dictyostelium: G-proteins activate separate Ras pathways using specific RasGEFs

Kae, Helmut, Kortholt, Arjan, Rehmann, Holger, Insall, Robert H, Van Haastert, Peter J M, Spiegelman, George B, Weeks, Gerald

Journal:

Year:

2007

Language:

english

File:

PDF, 168 KB

english, 2007

40

Phylogeny of the CDC25 homology domain reveals rapid differentiation of Ras pathways between early animals and fungi

Teunis J.P. van Dam, Holger Rehmann, Johannes L. Bos, Berend Snel

Journal:

Cellular Signalling

Year:

2009

Language:

english

File:

PDF, 1.29 MB

english, 2009

41

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

Sung-Jun Park, Faiyaz Ahmad, Andrew Philp, Keith Baar, Tishan Williams, Haibin Luo, Hengming Ke, Holger Rehmann, Ronald Taussig, Alexandra L. Brown, Myung K. Kim, Michael A. Beaven, Alex B. Burgin, Vi

Journal:

Year:

2012

Language:

english

File:

PDF, 1.05 MB

english, 2012

42

Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes

Pereira, Laëtitia, Rehmann, Holger, Lao, Dieu Hung, Erickson, Jeffrey R., Bossuyt, Julie, Chen, Ju, Bers, Donald M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.45 MB

english, 2015

43

Epac-Inhibitors: Facts and Artefacts

Rehmann, Holger

Journal:

Scientific Reports

Year:

2013

Language:

english

File:

PDF, 503 KB

english, 2013

44

Handbook of Cell Signaling || Epac, cAMP-Regulated Guanine Nucleotide Exchange Factors for Rap1 and Rap2

Rehmann, Holger

Year:

2010

Language:

english

File:

PDF, 995 KB

english, 2010

45

Specificity of commonly used cyclic nucleotides with PKA, PKG and Epac-implementing microcalorimetry to determine PDE activities

Joseph A Beavo, Johannes L Bos, Elke Butt, Stein O Doskeland, Hans-Gottfried Genieser, Thomas R Hinds, Heiko Poppe, Holger Rehmann, Sergei D Rybalkin, Frank Schwede, Xiao-Bo Tang

Journal:

BMC Pharmacology

Year:

2007

Language:

english

File:

PDF, 419 KB

english, 2007

46

GEFs and GAPs: Critical Elements in the Control of Small G Proteins

Johannes L. Bos, Holger Rehmann, Alfred Wittinghofer

Journal:

Year:

2007

Language:

english

File:

PDF, 2.35 MB

english, 2007

47

Synthesis and Biochemical Evaluation of Non-Cyclic Nucleotide Exchange Protein Directly Activated by cAMP 1 (EPAC1) Regulators

Wang, Pingyuan, Luchowska-StaÅska, Urszula, van Basten, Boy, Chen, Haiying, Liu, Zhiqing, Wiejak, Jolanta, Whelan, Padraic, Morgan, David, Lochhead, Emma, Barker, Graeme, Rehmann, Holger, Yarwood, St

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 1.70 MB

2020

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